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Recommended Sailings

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  • American West
    5 rating out of 5  (1 reviews)

    7 Night Columbia & Snake Rivers

    American West

    Departing from: Portland, Oregon
    Ports of Call:
    • Hayden Island, Portland, Oregon
    • Astoria, Oregon
    • Mount St. Helens, Washington
    • Cruise Columbia River, Pacific Northwest, Usa
    • The Dalles, Oregon
    • Pendleton, Oregon
    • Cruise Snake River, Pacific Northwest, Usa
    • Clarkston, Washington
    Sailing Dates:
    • July 2024
    • August 2024
    • September 2024
    • October 2024
    interior from
    Not Available
    oceanview from
    $3,965
    $566pernight
    balcony from
    $4,960
    $709pernight
    suite from
    $7,205
    $1,029pernight
    All the Cruise Line Offers & More:
    • Complimentary Dining, Cocktail Parties and More
     
    Riverview from $3,965
    ($566pernight)
    5 rating out of 5  (1 reviews)

American Cruise Lines

  • American Independence
    4.6 rating out of 5  (8 reviews)

    7 Night Historic South & Golden Isles

    American Independence

    Departing from: Jacksonville, Florida
    Ports of Call:
    • Amelia Island, Florida
    • Jekyll Island, Georgia
    • Savannah, Georgia
    • Hilton Head Island, South Carolina
    • Beaufort, South Carolina
    • Charleston, South Carolina
    Sailing Dates:
    • November 2024
    interior from
    Not Available
    oceanview from
    $3,965
    $566pernight
    balcony from
    $4,960
    $709pernight
    suite from
    $7,205
    $1,029pernight
    All the Cruise Line Offers & More:
    • Complimentary Dining, Cocktail Parties and More
     
    Riverview from $3,965
    ($566pernight)
    4.6 rating out of 5  (8 reviews)
  • American Splendor
    4.3 rating out of 5  (3 reviews)

    7 Night Lower Mississippi River

    American Splendor

    Departing from: New Orleans, Louisiana
    Ports of Call:
    • Houmas House Plantation, Louisiana
    • Baton Rouge, Louisiana
    • St. Francisville, Louisiana
    • Natchez, Mississippi
    • Vicksburg, Mississippi
    • River Cruising
    • Memphis, Tennessee
    Sailing Dates:
    • May 2024
    • June 2024
    • November 2024
    interior from
    Not Available
    oceanview from
    $4,125
    $589pernight
    balcony from
    $4,735
    $676pernight
    suite from
    $7,365
    $1,052pernight
    All the Cruise Line Offers & More:
    • Complimentary Dining, Cocktail Parties and More
     
    Was $5,735 – Save up to 17%
    Riverview from $4,125
    ($589pernight)
    4.3 rating out of 5  (3 reviews)
  • American Splendor
    4.3 rating out of 5  (3 reviews)

    7 Night Tennessee Rivers

    American Splendor

    Departing from: Chattanooga, Tennessee
    Ports of Call:
    • Decatur, Alabama
    • Florence, Alabama
    • Savannah, Tennessee
    • Paducah, Kentucky
    • Clarksville, Tennessee
    • Nashville, Tennessee
    Sailing Dates:
    • August 2024
    • September 2024
    • August 2025
    interior from
    Not Available
    oceanview from
    $4,125
    $589pernight
    balcony from
    $4,635
    $662pernight
    suite from
    $7,290
    $1,041pernight
    All the Cruise Line Offers & More:
    • Complimentary Dining, Cocktail Parties and More
     
    Was $5,635 – Save up to 18%
    Riverview from $4,125
    ($589pernight)
    4.3 rating out of 5  (3 reviews)
  • American Splendor
    4.3 rating out of 5  (3 reviews)

    7 Night Music Cities

    American Splendor

    Departing from: Nashville, Tennessee
    Ports of Call:
    • Clarksville, Tennessee
    • Dover, Tennessee
    • River Cruising
    • Paducah, Kentucky
    • River Cruising
    • Memphis, Tennessee
    Sailing Dates:
    • June 2024
    • July 2024
    • September 2024
    • October 2024
    interior from
    Not Available
    oceanview from
    $4,125
    $589pernight
    balcony from
    $4,735
    $676pernight
    suite from
    $7,365
    $1,052pernight
    All the Cruise Line Offers & More:
    • Complimentary Dining, Cocktail Parties and More
     
    Was $5,735 – Save up to 17%
    Riverview from $4,125
    ($589pernight)
    4.3 rating out of 5  (3 reviews)
  • American Spirit
    4.7 rating out of 5  (11 reviews)

    7 Night Puget Sound & San Juan Islands

    American Spirit

    Departing from: Seattle, Washington
    Ports of Call:
    • Anacortes, Washington
    • Friday Harbor, San Juan Island, Washington
    • Cruise San Juan Islands
    • Victoria, British Columbia
    • Port Townsend, Washington
    • Poulsbo, Washington
    Sailing Dates:
    • May 2024
    • June 2024
    • July 2024
    • August 2024
    • September 2024
    • October 2024
    interior from
    Not Available
    oceanview from
    $4,730
    $676pernight
    balcony from
    $5,210
    $744pernight
    suite from
    $5,030
    $719pernight
    All the Cruise Line Offers & More:
    • Complimentary Dining, Cocktail Parties and More
     
    Was $6,210 – Save up to 16%
    Riverview from $4,730
    ($676pernight)
    4.7 rating out of 5  (11 reviews)
  • American Independence
    4.6 rating out of 5  (8 reviews)

    7 Night Chesapeake Bay

    American Independence

    Departing from: Baltimore, Maryland
    Ports of Call:
    • Yorktown, Virginia
    • Crisfield, Maryland
    • Cambridge, Maryland
    • St. Michaels, Maryland
    • Annapolis, Maryland
    Sailing Dates:
    • October 2024
    interior from
    Not Available
    oceanview from
    $4,425
    $632pernight
    balcony from
    $5,385
    $769pernight
    suite from
    $7,900
    $1,129pernight
    All the Cruise Line Offers & More:
    • Complimentary Dining, Cocktail Parties and More
     
    Was $5,525 – Save up to 20%
    Riverview from $4,425
    ($632pernight)
    4.6 rating out of 5  (8 reviews)
  • American Star
    4.5 rating out of 5  (9 reviews)

    7 Night New England Islands

    American Star

    Departing from: Providence, Rhode Island
    Ports of Call:
    • New Bedford, Massachusetts
    • Nantucket, Massachusetts
    • Martha's Vineyard, Massachusetts
    • Block Island, Rhode Island
    • Newport, Rhode Island
    • Bristol, Rhode Island
    Sailing Dates:
    • June 2024
    • July 2024
    • August 2024
    • September 2024
    interior from
    Not Available
    oceanview from
    $4,540
    $649pernight
    balcony from
    $5,670
    $810pernight
    suite from
    $8,220
    $1,174pernight
    All the Cruise Line Offers & More:
    • Complimentary Dining, Cocktail Parties and More
     
    Riverview from $4,540
    ($649pernight)
    4.5 rating out of 5  (9 reviews)
  • American Independence
    4.6 rating out of 5  (8 reviews)

    7 Night Maine Coast & Harbors

    American Independence

    Departing from: Portland, Maine
    Ports of Call:
    • Bar Harbor, Maine
    • Bangor, Maine
    • Camden, Maine
    • Rockland, Maine
    • Boothbay, Maine
    • Bath, Maine
    Sailing Dates:
    • July 2024
    • August 2024
    • September 2024
    • September 2025
    interior from
    Not Available
    oceanview from
    $4,540
    $649pernight
    balcony from
    $5,670
    $810pernight
    suite from
    $8,220
    $1,174pernight
    All the Cruise Line Offers & More:
    • Complimentary Dining, Cocktail Parties and More
     
    Riverview from $4,540
    ($649pernight)
    4.6 rating out of 5  (8 reviews)
  • American Constellation
    4.9 rating out of 5  (7 reviews)

    7 Night Puget Sound & San Juan Islands

    American Constellation

    Departing from: Seattle, Washington
    Ports of Call:
    • Anacortes, Washington
    • Friday Harbor, San Juan Island, Washington
    • Cruise San Juan Islands
    • Victoria, British Columbia
    • Port Townsend, Washington
    • Poulsbo, Washington
    Sailing Dates:
    • October 2024
    • April 2025
    • May 2025
    interior from
    Not Available
    oceanview from
    $4,585
    $655pernight
    balcony from
    $5,405
    $772pernight
    suite from
    $6,935
    $991pernight
    All the Cruise Line Offers & More:
    • Complimentary Dining, Cocktail Parties and More
     
    Was $6,405 – Save up to 16%
    Riverview from $4,585
    ($655pernight)
    4.9 rating out of 5  (7 reviews)
  • American Serenade

    7 Night Music Cities

    American Serenade

    Departing from: Nashville, Tennessee
    Ports of Call:
    • Clarksville, Tennessee
    • Dover, Tennessee
    • River Cruising
    • Paducah, Kentucky
    • River Cruising
    • Memphis, Tennessee
    Sailing Dates:
    • November 2024
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    $5,075
    $725pernight
    suite from
    $7,005
    $1,001pernight
    All the Cruise Line Offers & More:
    • Complimentary Dining, Cocktail Parties and More
     
    Was $6,075 – Save up to 16%
    Balcony from $5,075
    ($725pernight)
  • American Serenade

    7 Night Tennessee Rivers

    American Serenade

    Departing from: Chattanooga, Tennessee
    Ports of Call:
    • Decatur, Alabama
    • Florence, Alabama
    • Savannah, Tennessee
    • Paducah, Kentucky
    • Clarksville, Tennessee
    • Nashville, Tennessee
    Sailing Dates:
    • October 2024
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    $5,075
    $725pernight
    suite from
    $7,005
    $1,001pernight
    All the Cruise Line Offers & More:
    • Complimentary Dining, Cocktail Parties and More
     
    Was $6,075 – Save up to 16%
    Balcony from $5,075
    ($725pernight)
  • American Eagle
    5 rating out of 5  (1 reviews)

    7 Night Historic South & Golden Isles

    American Eagle - New Ship!

    Departing from: Jacksonville, Florida
    Ports of Call:
    • Amelia Island, Florida
    • Jekyll Island, Georgia
    • Savannah, Georgia
    • Hilton Head Island, South Carolina
    • Beaufort, South Carolina
    • Charleston, South Carolina
    Sailing Dates:
    • December 2024
    interior from
    Not Available
    oceanview from
    $6,510
    $930pernight
    balcony from
    $6,960
    $994pernight
    suite from
    $7,880
    $1,126pernight
    All the Cruise Line Offers & More:
    • Complimentary Dining, Cocktail Parties and More
     
    Was $7,960 – Save up to 13%
    Riverview from $6,510
    ($930pernight)
    5 rating out of 5  (1 reviews)
  • American Song
    5 rating out of 5  (3 reviews)

    10 Night Northwest Pioneers

    American Song

    Departing from: Portland, Oregon
    Ports of Call:
    • Hayden Island, Portland, Oregon
    • Astoria, Oregon
    • Mount St. Helens, Washington
    • Cruise Columbia River, Pacific Northwest, Usa
    • Stevenson, Washington
    • Hood River, Oregon
    • The Dalles, Oregon
    • Richland (Tri-Cities), Washington
    • Pendleton, Oregon
    • Cruise Snake River, Pacific Northwest, Usa
    • Clarkston, Washington
    Sailing Dates:
    • June 2024
    • September 2024
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    $7,745
    $775pernight
    suite from
    $11,190
    $1,119pernight
    All the Cruise Line Offers & More:
    • Complimentary Dining, Cocktail Parties and More
     
    Balcony from $7,745
    ($775pernight)
    5 rating out of 5  (3 reviews)
  • American Constellation
    4.9 rating out of 5  (7 reviews)

    14 Night Alaska Inside Passage

    American Constellation

    Departing from: Seattle, Washington
    Ports of Call:
    • Anacortes, Washington
    • Friday Harbor, San Juan Island, Washington
    • Cruise Queen Charlotte Sound, British Columbia
    • Cruise Inside Passage, Alaska
    • Ketchikan, Alaska
    • Wrangell, Alaska
    • Petersburg, Alaska
    • Cruise Tracy Arm Fjord, Alaska
    • Cruise Glacier Bay National Park
    • Haines, Alaska
    • Skagway, Alaska
    • Juneau, Alaska
    Sailing Dates:
    • May 2025
    interior from
    Not Available
    oceanview from
    $10,385
    $742pernight
    balcony from
    $12,240
    $874pernight
    suite from
    $15,570
    $1,112pernight
    All the Cruise Line Offers & More:
    • Complimentary Dining, Cocktail Parties and More
     
    Was $11,385 – Save up to 9%
    Riverview from $10,385
    ($742pernight)
    4.9 rating out of 5  (7 reviews)

See the U.S. Like Never Before Aboard American Cruise Lines

Explore the Sweet Land of Liberty Anew with River and Ocean Cruises Visiting 28 States

Set sail on the adventure of a lifetime aboard a small cruise ship or riverboat with ample amenities and top-notch service delivered by an all-American crew. A relaxed, casual atmosphere combined with an unparalleled attention to detail will make you feel right at home from the beginning to the end of your journey.

New England itineraries take you to charming seaside towns and islands, cruising the coast from Newport, Rhode Island up to Bar Harbor, Maine. Dive into the area's rich maritime history and taste some of the nation's best seafood along the way.

Across the country to the West Coast, you'll find American Cruise Lines river and ocean sailings to take you through the Pacific Northwest and Alaska. Set out on the very same trail that Lewis and Clark once traversed, see pods of orcas swimming in the Puget Sound, or sample delicious wines in wine country. Each itinerary offers so much to explore.

Sailing the Mississippi is a unique adventure all its own. With river cruises spanning St. Louis, Missouri to St. Paul, Minnesota and Memphis, Tennessee to New Orleans, Louisiana, there's so much to do and see. Visit old plantations and Civil War battlefields, tour the hometown of Mark Twain, and indulge in blues and BBQ.

Experience southern hospitality at its finest aboard Southeast cruises navigating the Intracoastal Waterway and Chesapeake Bay. Historic landmarks and local treasures abound from the great rivers of Florida to the Golden Isles and beyond.

With exceptional cuisine, daily entertainment, and complimentary experiences, traveling aboard an American Cruise Lines world-class ship is a remarkable experience you'll never forget. Book now to begin your next adventure of the United States.